Inhibition of Mycobacterium-RmlA by Molecular Modeling, Dynamics Simulation, and Docking
نویسندگان
چکیده
منابع مشابه
Inhibition of Mycobacterium-RmlA by Molecular Modeling, Dynamics Simulation, and Docking
The increasing resistance to anti-tb drugs has enforced strategies for finding new drug targets against Mycobacterium tuberculosis (Mtb). In recent years enzymes associated with the rhamnose pathway in Mtb have attracted attention as drug targets. The present work is on α-D-glucose-1-phosphate thymidylyltransferase (RmlA), the first enzyme involved in the biosynthesis of L-rhamnose, of Mtb cell...
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ژورنال
عنوان ژورنال: Advances in Bioinformatics
سال: 2016
ISSN: 1687-8027,1687-8035
DOI: 10.1155/2016/9841250